Lung Cancer

PASADENA, Calif. , Sept. 10, 2021 /PRNewswire/ -- Promis Diagnostics, Inc., a molecular diagnostics company focused on early cancer diagnosis, recently presented clinical validation data for CystoChek, its proprietary urine-based DNA methylation test of PENK for bladder cancer (BCa) detection in hematuria, at the 2021 American Urological Association (AUA) Annual Meeting. Researchers from Genomictree Inc, Chungnam National University Hospital (Daejeon, South Korea ), and Promis previously discovered that aberrant methylation of PENK, a potential biomarker, frequently occurs in bladder cancer. To further demonstrate the validity of their discovery, and to evaluate the performance of CystoChek, two separate clinical studies were conducted. First, in a retrospective study, the data showed a sensitivity of 91.0% with a specificity of 93.5% in detecting Ta high-grade and greater stages of BCa in 567 hematuria patients. Second, in a prospective study, the data demonstrated a sens

Neuroendocrine cells are specialized cells found in many parts of the body, including the gastrointestinal (GI) tract, gallbladder, and lungs. These cells receive signals from the brain to produce and release certain hormones that control many of our body functions. Neuroendocrine tumors (NETs) happen when neuroendocrine cells become overactive and cancerous. NETs usually involve the GI tract and the lungs. Small cell lung cancer (SCLC), also called oat cell cancer, accounts for 10–15% of all lung cancers. It is also the most prevalent type of neuroendocrine lung tumor. Share on Pinterest Coloured X-ray showing the blood vessels in a lung. Science Photo Library/Getty Images Neuroendocrine lung tumors are a family of tumors that arise from the cells that line the bronchi and other parts of the lung. This disease group has distinct clinical and pathological characteristics, and varies in cell structure, features, appearance, presence of dead cells (necrosis), and the number of dividing c

According to Ashley E. Ross, MD, PhD, an associate professor of urology at Northwestern Medicine, advances have been made in how we detect and determine the extent of prostate cancer disease burden. Much of this has come from the implementation of imaging. This includes the use of multi-parametric MRI prior to initial diagnostic biopsy for men with suspected prostate cancer and additionally the use of PET imaging to determine whether metastatic disease is present. Further, regarding treatment, precision medicine and targeted therapeutics are playing an increasing role in management of metastatic disease. In an interview with Targeted Oncology , Ross discusses new prostate cancer screening and staging options as well as therapies for both earlier and later-stage disease.  TARGETED ONCOLOGY: What most important developments over the past year are reshaping the landscape of diagnosed prostate cancer? ROSS: Prostate cancer continues to be the most common non-skin malignancy among

Lung adenocarcinoma is the most common type of lung cancer in the United States. It makes up about 40 percent of lung cancers. Lung adenocarcinoma falls into a group of cancers called non-small cell lung cancers. They're named for the way their cells appear under a microscope. Lung adenocarcinoma progresses more slowly than other lung cancers. It occurs more often in women . In this article, we take a look at how lung adenocarcinoma is treated, what causes it, and how to recognize its symptoms. Lung adenocarcinoma doesn't usually cause obvious symptoms in the early stages. The tumor may develop over quite some time until you experience general symptoms such as: Most of these symptoms can have many potential causes. It's a good idea to visit a healthcare professional any time you develop any of these symptoms to rule out lung cancer. Late stage symptoms As lung cancers progress, symptoms tend to get worse and lead to a rapid decline in quality of life. In the late stages, l

The results of a systematic review found that the risk of recurrent or new cancer is not increased with the incorporation of biologic disease-modifying anti-rheumatic drugs (bDMARDs) for rheumatoid arthritis (RA) compared with no bDMARDs, apart from skin cancers including melanoma. This study is the first meta-analysis that evaluated the risk of recurrent or new cancers in patients with chronic inflammatory arthritis (CIA) and a history of neoplasia who were exposed to biologic or targeted synthetic disease-modifying anti-rheumatic drugs. The Motivation Biologic disease-modifying anti-rheumatic drugs have positively changed the treatment of rheumatoid arthritis by achieving remission and improving quality of life. After this success, these treatments were utilized in the treatment of other chronic inflammatory arthritis diseases including axial spondyloarthritis (AS) and psoriatic arthritis (PsA). Targeted synthetic disease-modifying anti-rheumatic drugs (tsDMARDs) emerged as a new the

Skin cancer is the most common form of cancer in the United States, with 1 in 5 Americans estimated to develop it in their lifetime.  Most scalp tumors are benign—in fact, only 1-2% are malignant and 13% of malignant skin cancers affect the scalp. Some people are at higher risk of developing skin cancer; however, it can affect anyone.   It can affect all skin tones and is most likely to occur in areas of the skin that are exposed to the sun. AndreyPopov / iStock / Getty Images Types of Skin Cancer on the Scalp Different types of skin cancer can develop on your scalp. The two most common skin cancer types, basal cell carcinoma and squamous cell carcinoma, are considered highly curable. Melanoma is a rarer and more aggressive form of skin cancer. Basal Cell Carcinoma Basal cell carcinoma (non-melanoma malignancy) is the most common form of skin cancer. It starts in the basal cell layer of the epidermis (the outer t

Doctors evaluate the size, location, and spread of tumors to determine what stage the cancer is. Lung cancer is identified by numbered stages 0 through 4, as it progresses, with subcategories within each stage. The treatment for lung cancer depends on the stage. After you receive a lung cancer diagnosis, your doctor will want to find out where the cancer is in your body. This process is called staging. Learning whether and where your cancer has spread can help your doctor find the right treatment for you. Your stage also helps provide an outlook. Your doctor will assign your lung cancer a clinical stage based on the results of: your physical exam your biopsy imaging tests such as a computed tomography (CT) scan and magnetic resonance imaging (MRI) If you have surgery, your doctor will also give your cancer a pathological or surgical stage. The doctor finds this stage by examining the tissue removed during the biopsy. Lung cancers are divided into two main types: small cell lung cancers

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Hospitals will share expertise and resources to enable early detection, treatment of lung cancer September 14, 2021 – Northwest Medical Center in Margate, Fla. and Westside Regional Medical Center in Plantation, Fla. announced the launch of their joint multidisciplinary screening program aimed at early detection and treatment of lung cancer. As affiliate hospitals of HCA Healthcare, Northwest and Westside are able to draw upon extensive shared resources, including experts in thoracic surgery, radiation oncology, pathology and radiology, to ensure patients receive the right care at the right time. Accounting for 23 percent of all cancer-related deaths, lung cancer is the leading cause of death by cancer in the U.S. Early screening can enable the early detection, diagnosis and treatment of the disease, preventing its spread and ultimately improving chances of survival for patients. Recently, millions of preventative health screenings, including lung cancer screenings, we

In 2015, Tabitha Paccione developed a cough that just never went away. As an elementary school teacher, she assumed it was just a bug she picked up from her students. When it persisted, she visited a doctor and in 2016 she learned something shocking: She had stage 4 lung cancer. Paccione, then 35, wondered how this was possible. "I'm young. I've never smoked. I'm active. I don't have a history of cancer," Paccione, from Cypress, California, told TODAY. "There are moments in your life where you are just overcome with so much fear and heartbreak you kind of black out. I remember sitting in that doctor's office after he said the words 'lung cancer' and I just completed blanked." Since learning she has stage 4 lung cancer, Tabitha Paccione has been dedicated to making memories with her family. They regularly go on road trips and take adventures together. Courtesy Tabitha Paccione While she felt scared, worried and sad, Paccione decided to emb

Melanoma is a kind of cancer that begins in the skin cells that create the pigment melanin. Melanoma usually starts as a dark mole on the skin. However, it can also form in other tissue, such as the eye or mouth. It's important to keep an eye on moles and changes in your skin, as melanoma can be deadly if it spreads. There were more than 10,000 deaths from melanoma in the United States in 2016. Melanoma stages are assigned using the TNM system. The stage of the disease indicates how much the cancer has progressed by taking into account the size of the tumor, whether it's spread to lymph nodes, and whether it's spread to other parts of the body. A doctor can identify a possible melanoma during a physical exam and confirm the diagnosis with a biopsy, where the tissue is removed to determine if it's cancerous. But more sophisticated technology, such as PET scans and sentinel lymph node biopsies, are necessary to determine the cancer's stage or how far it's progress

COVID-19 is a respiratory disease caused by a type of coronavirus that emerged in late 2019 called SARS-CoV-2. Most people with COVID-19 develop mild illness. Older adults and people with existing conditions like diabetes, cancer, or kidney disease are at the highest risk of developing severe symptoms. It's estimated that more than 80 percent of COVID-19 deaths are in people over 65. The coronavirus can attack your lungs and heart. It can cause chest pain or a burning sensation in your lungs. The Centers for Disease Control and Prevention (CDC) lists persistent pain or pressure in your chest as a sign that you should seek emergency medical care for COVID-19. Keep reading to learn why COVID-19 sometimes causes chest pain and when you should seek medical attention. Medical emergency Burning in your chest can have many potential causes that range from mild to life threatening. Visit a doctor right away if your chest pain is intense or accompanied by other concerning symptoms. It'