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Showing posts from May, 2022

MIA and melanoma: Definitions, links, and detecting melanoma - Medical News Today

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Melanoma is a type of cancer that involves the uncontrolled growth of abnormal skin cells. In the future, a protein called melanoma inhibitory activity (MIA) may help doctors identify individuals who have melanoma or an increased risk of the condition. The presence of MIA in the body may signal the onset of melanoma in certain cases. This is because melanoma cells secrete MIA. The MIA gene controls the expression of these proteins. However, further research into MIA and melanoma is necessary. Melanoma is the most dangerous type of skin cancer. According to the American Cancer Society, healthcare professionals diagnose just under 100,000 new cases of melanoma each year in the United States. The risk of developing melanoma increases with age, but it can affect people from all age groups. This article discusses the key characteristics of the MIA gene and melanoma. It also explores the relationship between MIA and melanoma, including how MIA levels may help doctors detect melanoma in th...

A Case of Bullous Pemphigoid Associated With Nivolumab Therapy - Cureus

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This is a case report of new-onset bullous pemphigoid after the initiation of nivolumab for melanoma. Bullous pemphigoid is a rare immune-mediated adverse effect of nivolumab, with fewer than a hundred cases described. The patient initially developed a rash, which later progressed to respiratory symptoms, prompting the discontinuation of nivolumab. He was started on oral steroids, which improved his symptoms. However, while being tapered off the steroids, his rash reoccurred with the development of bullous pemphigoid. The diagnosis was confirmed by increased eosinophils and sub-epidermal vesicle formation compatible with bullous pemphigoid on skin biopsy. The patient was treated with steroids, mycophenolate, doxycycline, and niacinamide with significant improvement in his symptoms. Introduction Nivolumab is an immunoglobin G4 monoclonal antibody that works as a checkpoint inhibitor by preventing programmed cell death 1 ligand from binding, disrupting T cell regulation. This i...

Lung cancer symptoms: The one little known sign that could mean you have it - My London

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Lung cancer is the most common cause of cancer death in the UK, with around 35,100 cancer deaths each year. According to Cancer Research UK, It's estimated that 96 people die each day from the disease, and it accounts for 21 per cent of all cancer deaths. The danger with lung cancer is that there are usually no signs or symptoms in the early stages, and symptoms develop as the condition progresses. The most commonly reported symptoms include shortness of breath, wheezing, chest infections and having a persistent cough with blood or phlegm. On the NHS website, they also list loss of appetite or unexplained weight loss and persistent tiredness. However there is one symptom that could be an early tell-tale sign that is not a respiratory sign of the illness, and can appear on your fingertips. Here's everything you need to know. READ MORE: Bowel cancer: Little-known signs you could have it from bloating to weight loss as Prince William and Kate donate to Deborah James fund Wha...

Is Aloe Vera Juice a Cure for Lung Cancer? - Healthline

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Aloe vera is a medicinal plant known for its therapeutic purposes. The leaves of this succulent contain a clear gel that's sometimes applied topically. Aloe vera can also be taken orally, and many people even enjoy drinking aloe vera juice. Aloe vera juice is believed to help improve the immune system, and some people claim that it can treat lung cancer. Here's what you need to know about aloe vera and lung cancer, including whether aloe vera juice is an effective treatment. Lung cancer develops when malignant cells grow unmanaged and form a tumor in the lungs. Common symptoms include coughing, wheezing, and chest pain. Typical treatments for lung cancer include chemotherapy, radiation, surgery, and targeted drug therapy. However, some people also consider aloe vera juice a cancer treatment. This is likely due to aloe vera containing acemannan, a chemical compound with anti-inflammatory, antiviral, and anticancer properties. It's believed to also have a tumor suppressant ef...

Stranger in park helps woman spot potentially deadly skin cancer - WJXT News4JAX

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Between caring for her two beautiful little girls and being a special education teacher, Melissa Albin admits she hasn't always made her health a priority. "Mom and teacher came before me," said Albin. But, that all changed last year after a chance encounter with a stranger at the park. "It was a warm day, I was wearing a tank top. And I was watching them over on the playground and I had my arms up on the stroller and I noticed a woman off to the side who kept looking at me," she recalled. Albin wasn't sure what to think, but the woman finally came over to her. "She approached me and she said I am really sorry if this is odd, but I want to let you know I am a dermatologist and I have been looking at that mole on your arm and it's really alarming to me," she said. Albin had been previously warned by her general practitioner to get the mole checked out but never followed up. However, she didn't hesitate to book an appointment this time around...

Early palliative care for people with non-small cell lung cancer - Medical News Today

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Metastatic non-small cell lung cancer (NSCLC) happens when NSCLC spreads to other parts of the body. There is no cure yet, but early treatment and palliative care can improve outcomes for many people. Palliative care involves people receiving long-term care for a serious illness that has no cure yet. Treatment usually relies on extending life and relieving symptom discomfort. There are many early palliative care options for people with NSCLC, including both emotional and physical care. This article looks at what treatment options are available, and how beneficial early palliative care can be in improving quality of life. Palliative care takes a number of different approaches, but focuses on the following areas: Physical symptoms Common physical symptoms include: pain fatigue reduced appetite nausea and vomiting shortness of breath insomnia coughing up blood constipation External beam radiation for someone living with NSCLC can improve their quality of life and relieve symptoms such as...

CBD Oil for Skin Cancer – Benefits & Top Brands of 2022 - Health Behavior News Service

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While CBD oil isn't the forefront treatment for skin cancer, there's evidence that supports its use as an adjunctive therapy and a way to deal with the nasty side effects of chemotherapy. CBD has been making big headlines in the skincare space, but now it's being examined as a potential therapeutic compound in the treatment of a wide range of skin conditions, including cancer. Previously, research has shown that CBD can help people with epilepsy, loss of appetite or anorexia, irritable bowel syndrome, and various types of autoimmune disorders. While there are plenty of CBD-based topical products out there, not all CBD extracts are sourced the same — and that's the biggest problem on the market right now. Fortunately, there are several reputable companies that you can turn to if you're looking for the best CBD oils to use for skin cancer. In this article, I leave no stone unturned while exploring CBD's potential in that regard. CBD Oil for Skin Cancer...

A Decade of Transformation in Melanoma Treatments - Targeted Oncology

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When Keith T. Flaherty began treating patients with advanced melanoma 2 decades ago, his recommendation was simple: If you're eligible, enroll in a clinical trial. As late as 2010, only 2 FDA-approved therapies existed for the treatment of advanced melanoma: the chemotherapy dacarbazine and high-dose (HD) IL-2. A review of 3 dacarbazine trials reported response rates of 10% to 15% and overall survival (OS) of 8 months. 1 An analysis of HD IL-2 treatment reported a response rate of 16% and severe toxicity but also a durable response rate of just under 5% of patients. 2,3 "We would immediately follow discussions of the approved therapies by talking about investigational therapies. Essentially any investigational therapy was on the table, even ones that were absolutely brand new, just starting phase 1 trials, with or without rationale as to why they were a good fit for melanoma," said Flaherty, director of the Henri and Belinda Termeer Center for Targeted Therapy and direct...