stage 4 small cell :: Article Creator Positive Trials Continue To Shape The SCLC Treatment Landscape In an interview with Targeted Oncology, Ariel Lopez-Chavez, MD, discussed recent developments in the small cell lung cancer space. Recent advancements in small cell lung cancer (SCLC) treatments have introduced transformative therapies and trial results, according to Ariel Lopez-Chavez MD. Notably, the FDA granted accelerated approved to tarlatamab-dlle (Imdelltra), a bispecific T-cell engager (BiTE) for the treatment of SCLC that has progressed on or after platinum-based chemotherapy, in May 2024, offering a new option for patients with second-line SCLC.1 This approval was based on findings from the phase 2 DeLLphi-301 study (NCT05060016).2 Additionally, positive findings from trials like ADRIATIC (NCT03703297) and IMforte (NCT05091567) are further shaping treatment approaches. In extensive-stage SCLC, immune checkpoint inhibitors atez