Lung Cancer

A teratoma is a rare type of germ cell tumor (GCT) that may contain different types of tissue. These tumors occur most commonly in the ovaries, testicles, and tailbone. However, they can occur elsewhere in the body. Teratomas are a type of GCT. This term refers to a tumor that develops from germ cells , which are the cells that develop into the cells that make up the male and female reproductive systems. This is why teratomas commonly occur in the testes and ovaries. However, germ cells can migrate to other parts of the body and develop into tumors known as extragonadal germ cell tumors . Teratomas can appear in newborns, children, or adults. They may be benign, meaning noncancerous, or malignant. The treatment plan for a teratoma will typically involve surgery. In this article, we discuss teratomas in more detail, including the symptoms, causes, diagnosis, and treatment of this type of tumor. A teratoma is a type of tumor that may contain many different tissues. Its name comes from t...

Leveraging EGFR TKIs as a backbone for combination therapies will be pivotal for expanding treatment options and delivering more personalized therapies in the first-line setting for patients with non–small cell lung cancer harboring EGFR mutations. Leveraging EGFR TKIs as a backbone for combination therapies will be pivotal for expanding treatment options and delivering more personalized therapies in the first-line setting for patients with non–small cell lung cancer (NSCLC) harboring EGFR mutations, according to Marina Garassino, MD. Single-agent osimertinib (Tagrisso) remains the standard of care for patients with EGFR exon 19 and 21 mutations after data from clinical trials showed the EGFR TKI improved progression-free survival (PFS) and penetrated the central nervous system. However, combinations under investigation could further shift the treatment paradigm, Garassino noted. "In the future, we have to tailor our treatments based on different types of mutations, the presence...

Saw palmetto (Serenoa repens) is a tree that grows up to 10 feet tall with thorn-shaped leaves arranged like a fan. It is high in healthy fats and has been used for centuries to improve prostate health, balance hormone levels, and prevent hair loss in men.  It can also block negative effects on your testosterone levels and the uptake of DHT and decrease its ability to bind to androgen receptors by nearly 50%.  In this article, we go over the 10 best saw palmetto supplements on the market, their benefits, and answer the most common questions about the supplement. Top 10 Saw Palmetto Supplements Tested/Ranked: Best Saw Palmetto Supplements Overall: Havasu Nutrition Saw Palmetto Best Value: Swanson Saw Palmetto Best for Men Over 40: Zhou Nutrition's Saw Palmetto Prostate Health Complex Best with Pumpkin Seed Oil: Essential Elements' Saw Palmetto Plus Best for Men: Sundown Naturals Saw Palmetto for Him Best for Women: Saw Palmetto by Nature's Craft Best Supe...

The use of avelumab (Bavencio) as first-line maintenance treatment was associated with long-term overall survival (OS) benefit in patients with advanced urothelial carcinoma who received avelumab with or without second-line treatment, according to a study presented at the 2022 American Society of Clinical Oncology Annual Meeting in Chicago, Illinois. 1 The JAVELIN Bladder 100 trial (NCT02603432) previously demonstrated that avelumab first-line maintenance and best supportive care (BSC) significantly prolonged OS compared with BSC alone in patients with advanced urothelial carcinoma that had not progressed with first-line platinum-containing chemotherapy. 2,3 For the current study, the investigators performed an exploratory analysis of outcomes in patients in the avelumab plus BSC arm based on receipt of second-line treatment, according to the study's poster. Patients in the trial had unresectable locally advanced or metastatic urothelial carcinoma that had not progressed with 4 to...

Basal cell carcinoma is a skin cancer that affects the basal cells. Basal cells are round cells in the epithelium, the outer layer of the skin. Basal cell carcinoma is the most common type of skin cancer. Basal cell carcinoma, or basal cell skin cancer, is a less aggressive cancer than melanoma. Still, it can grow into nearby tissues and bones if a person does not seek treatment. Basal cell carcinomas are often flesh-colored, making them less noticeable than some other cancers. A person might notice an unusual lump or bump, a waxy or scaly spot, or a skin-colored growth. There may be multiple changes to the skin or skin lesions. Regular skin checks and prompt treatment for any unusual growths on the skin can help a person identify basal cell carcinoma early and avoid serious complications. In rare cases, the condition can be fatal. Read on to learn more about the symptoms, diagnosis, causes, and treatments of basal cell carcinoma. The epidermis is the outer layer of skin, formed of sev...

Journal of Urology (2022). DOI: 10.1097/JU.0000000000002740"> Journal of Urology (2022). DOI: 10.1097/JU.0000000000002740" width="800" height="530"> RFS following Gem/Doce induction. Credit: Ian M. McElree et al, Journal of Urology (2022). DOI: 10.1097/JU.0000000000002740 A combination of two intravesical chemotherapy drugs—gemcitabine and docetaxel—yields high response rates with good tolerability in patients with high-risk non-muscle-invasive bladder cancer (NMIBC), reports a study in The Journal of Urology . The "Gem/Doce" combination provides a safe and effective alternative for treatment of high-risk NMIBC, according to recently published research by Vignesh Packiam, MD, and colleagues of University of Iowa Hospitals ...

Many tumors can be eliminated with surgery, chemotherapy, radiation, and other treatments. But once cancer spreads, or metastasizes, to other parts of the body, it becomes much harder to stop. In this Q&A, medical oncologist Emily Feld talks about how metastatic cancer is diagnosed and treated at Memorial Sloan Kettering Cancer Center (MSK). Dr. Feld, who sees patients at MSK Commack on Long Island, specializes in treating patients with genitourinary cancers, including tumors of the prostate, bladder, kidneys, and testicles. Metastatic cancer occurs when cancer cells spread from the organ where they started to a distant part of the body. Metastatic cancers are considered stage 4. Even after cancer has invaded another organ, it is still identified by the place where it developed. For example, prostate cancer that has spread to the bones is not the same as cancer that started in the bones, known as primary bone cancer (of which there are several types, inclu...

Astellas Korea said Wednesday that its prostate cancer treatment, Xtandi, (ingredient name: enzalutamide), will be covered by selective benefits in treating hormone-responsive metastatic prostate cancer (mHSPC) combined with androgen deprivation therapy (ADT). Astellas Korea's Xtandi will receive insurance coverage for all hormone-responsive metastatic prostate cancer patients. Xtandi is a prostate cancer treatment with the most indications among androgen receptor-targeted agents (ARTA) in Korea. It won domestic approval in June 2013 as metastatic castration-resistance prostate cancer (mCRPC) treatment and received approval to treat metastatic prostate cancer in 2021. This screening benefit of Xtandi is applied to all mHSPC patients (All Comer) progressive prostate cancer patients with remote metastasis, regardless of the volume or risk of the disease, Astellas Korea said. When mHSPC progresses to the metastatic castration-resistant prostate cancer (mCRPC) s...

Lung cancer is the leading cause of cancer-related deaths in the United States. District Health Department #10, along with local public health departments, healthcare organizations and health advocates around the country, are promoting World Lung Cancer Awareness Day, which is Aug. 1 every year. The mission for this day is to educate people about lung cancer while encouraging people to screen themselves for the disease. According to the World Health Organization, lung cancer is so prevalent in the world that, on an annual basis, more people die from lung cancer than from colon, breast and liver cancers combined. According to the American Lung Association: • Lung cancer-related deaths started to decline in 2016. However, lung cancer is still the leading cause of cancer-related deaths in the U.S. In 1987, it surpassed breast cancer as the...