Lung Cancer

Acral lentiginous melanoma (ALM) is a rare type of cutaneous skin cancer that develops on the palms of the hands, soles of the feet, and nail beds. Unlike most skin cancer, it is not associated with sun exposure. ALM accounts for 70% of melanomas in Black people, 46% in Asian people, and less than 10% in White people. When detected early, ALM can be cured by surgical removal. This procedure, called a wide local excision, is performed by a surgical oncologist (doctor specializing in the diagnosis and treatment of cancer) and is the mainstay of treatment for most ALM lesions.  If the cancer has spread, additional treatments, such as chemotherapy, may be needed. In this article, we will review the treatment options. Kateryna Kukota / iStock/ Getty Images Plus Surgeries and Specialist-Driven Procedures A team of dermatologists (doctors specializing in the diagnosis and treatment of disorders of the skin, hair, and nails), oncologis...

General Information Small cell lung cancer (SCLC) is a malignant epithelial neuroendocrine tumor consisting of small cells with scant cytoplasm, ill-defined cellular borders, finely granular nuclear chromatin, and absent or inconspicuous nucleoli. SCLC accounts for about 13%-15% of lung cancer cases; it can be further classified as pure SCLC or combined SCLC (with mixture of small and non-small cell histology) It is characterized by rapid doubling time, high growth fraction, and widespread metastases early in disease; patients often present with hematogenous metastases SCLC is suspected in patients with a history of cigarette smoking, coughing, hemoptysis, wheezing, dyspnea, and/or chest pain. Risk Factors for Lung Cancer Tobacco smoke Almost all cases of SCLC are related to tobacco use > 90% of cases occur in elderly current or past heavy smokers Risk of SCLC increases with increasing duration and intensity of smoking Environmenta...

Scientists at Newcastle University have identified the mechanism for skin cancer growth. Their research, published in the  British Journal of Dermatology , describes how early-stage melanomas at risk of spreading secrete a growth factor, called TGFβ2, which causes the reduction, or downregulation, of the proteins AMBRA1 and Loricrin, both of which are found in the skin overlaying the tumour. The growth factor TGFβ2 also causes the loss of claudin-1, which in turn leads to loss of skin integrity, facilitating ulceration. Senior author Professor Penny Lovat, Professor of Cellular Dermatology and Oncology at Newcastle University, and Chief Scientific Officer at AMLo Biosciences, explained: "AMBRA1, Loricrin and Claudin 1 are all proteins key to maintaining the integrity of the upper layer of the skin," and that the loss of these proteins causes gaps to develop, allowing the tumour to spread and ulcerate - a proce...

COVID-19 is a respiratory disease caused by a type of coronavirus that emerged in late 2019 called SARS-CoV-2. Most people with COVID-19 develop mild illness. Older adults and people with existing conditions like diabetes, cancer, or kidney disease are at the highest risk of developing severe symptoms. It's estimated that more than 80 percent of COVID-19 deaths are in people over 65. The coronavirus can attack your lungs and heart. It can cause chest pain or a burning sensation in your lungs. The Centers for Disease Control and Prevention (CDC) lists persistent pain or pressure in your chest as a sign that you should seek emergency medical care for COVID-19. Keep reading to learn why COVID-19 sometimes causes chest pain and when you should seek medical attention. Medical emergency Burning in your chest can have many potential causes that range from mild to life threatening. Visit a doctor right away if your chest pain is intense or accompanied by other concerning symptoms. It...

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Chemotherapy cream kills cancer cells in the skin. Because the body is less able to absorb the cream into the deep layers of the skin, it typically causes fewer side effects than oral or intravenous chemotherapy. This may make chemotherapy cream a suitable choice for early stage skin cancers and precancers. It may also be useful for eliminating human papillomavirus, which is a virus that can increase the risk of cancer, from the skin. This article will look at chemotherapy cream's uses, effectiveness, side effects, and alternatives. Chemotherapy cream is a topical ointment or cream that a person applies to the skin. Doctors commonly prescribe a drug called 5-fluorouracil (5FU). It works by killing fast growing skin cells, including cancer cells and cells that are dividing so quickly that they may become cancer. Some brand names for fluorouracil cream include: Efudex Fluoroplex Carac Tolak Topical chemotherapy penetrates the outer layers of the skin. Doctors usually prescribe it to ...

Home Health Cancer symptoms: Different sized pupils could be indicative of lung cancer Hello,