Top Questions About Non-Small Cell Lung Cancer - HealthCentral.com

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If your tumor has a "driver mutation" (cells that have a genetic mutation that is driving them to divide and spread), the first-line treatment is a drug in a category called targeted therapy, says Afshin Dowlati, M.D., a professor of medicine and oncology at Case Western Reserve University in Cleveland, OH. These drugs target that mutation and aim to halt cancer-cell growth. For example, osimertinib is the standard of care targeting an EGFR mutation, adds Dr. Dowlati.

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