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Successful Diagnosis and Treatment of Occult Prostate Cancer Despite Multiple Negative Prostate Biopsies and Negative Prostate MRIs - Cancer Network

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ABSTRACT Prostate-specific antigen (PSA) values above 100 ng/mL often suggest metastatic prostate cancer. We present the case of a patient with a PSA of 110 ng/mL, 4 negative prostate biopsies, and 4 negative prostate MRIs. After his fifth MRI revealed a PI-RADS 5 lesion, he underwent his fifth transrectal biopsy; this revealed Gleason 3 + 4 = 7. He was found to have organ-confined pT2 disease on subsequent radical prostatectomy pathology. This case highlights that there may be no PSA for which one can assume metastatic disease with certainty. Depending on life expectancy, patients with extremely elevated PSA may still warrant a full staging workup Introduction And Initial Presentation A man, aged 73 years, presented to our care in early 2021 with a prostate-specific antigen (PSA) of 110 ng/mL after 4 negative prostate biopsies and 4 negative prostate MRIs. His journey had begun in 2002 when his PSA was 3 ng/mL. Two years later, in 2004, at a PSA level of 3.8 ng/mL, he had his first tr...

Global Small Cell Lung Cancer Treatment Market 2022 Comprehensive Research Report and Forecast to 2028 – Business Merseyside - Business Merseyside

Market Research Place issued a study on the Global Small Cell Lung Cancer Treatment Market from 2022 to 2028 that comprises of the business intelligence, covering North America, Europe, Asia Pacific, and Middle East & Africa regions. Each section of the study provides detailed comprehension of the overall Small Cell Lung Cancer Treatment industry. The study has been segregated into market dynamics, type, application, regional, and competitive landscape. Factors influencing the market growth, potential opportunities, major challenges in the industry, and threats have been examined in the market dynamics section. Market size estimation and forecasts for type and application segment has been covered in the separate sections. Regional section throws light on the qualitative and quantitative insights by type and by application for all the major countries. DOWNLOAD FREE SAMPLE REPORT: https://www.marketresearchplace.com/report-detail/202342/request-sample Premium insights suc...

Are Achy Bones a Sign Prostate Cancer Has Metastasized? - Healthline

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Pain can often be a symptom of advanced prostate cancer, particularly pain felt deep in the bones. Since more than 60 percent of men with advanced prostate cancer will go on to develop bone metastases, or cancer cells that have spread to the bones, achy bones may be a sign that prostate cancer has metastasized. While achiness due to weakened bones can be quite painful, there are various ways to manage the pain. Here's what to be on the lookout for if you're concerned about metastatic prostate cancer, what bone pain really feels like, and how pain and discomfort can be treated. Metastatic prostate cancer is cancer that has spread to distant sites. This means cancer cells have escaped the prostate area and are spreading, or metastasizing. This advanced form of prostate cancer tends to spread to the lymph nodes first. It can also spread to the bloodstream, which leads to cancer cells being deposited in your bones. In fact, 85 to 90 percent of metastatic prostate cancer sees metas...

Aquablation: Surgical Robot Treats Enlarged Prostate - NBC4 Washington

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Health March 17, 2022 10:32 pm ","date_string_short":" Mar 17 ","eyebrow":{"link":"https:\/\/www.nbcwashington.com\/tag\/prostate\/","label":"prostate","sponsored":false},"title":"Aquablation: Surgical Robot Treats Enlarged Prostate","summary":" A new, minimally-invasive treatment option promises relief for men with enlarged prostates. News4’s Doreen Gentzler explains it doesn’t involve incisions and the potential side effects of surgery. \n","link":"https:\/\/www.nbcwashington.com\/news\/health\/aquablation-surgical-robot-treats-enlarged-prostate\/3002620\/","image":{"id":6...

Nonmalignant Etiologies of Back Pain Common With Metastatic Prostate Cancer - Oncology Nurse Advisor

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Many men with metastatic prostate cancer (mPC) have back pain associated with nonmalignant etiologies at sites of metastases. These findings were published in JCO Oncology Practice . For patients with mPC, the spine is the most common site of metastasis and can be a source of pain. These patients often receive tumor-directed therapies; however, nonmalignant etiologies of back pain would not be responsive to these interventions. To better understand back pain in mPC, data were sourced from the Memorial Sloan Kettering Cancer Center patient registry, collected between 2013 and 2017. Fifty-three men with mPC who reported pain in an area of metastastic disease were retrospectively reviewed for trends in back pain. The patients were median age 72 years (range, 52 to 90), 66% had castration-resistant disease, 64% had a precancer history of back pain, 72% had abnormal posture, 68% had reduced spinal range of motion, and 51% had gait abnormalities. Continue Reading ...

Lung cancer sign in feet: The little known symptom you shouldn't ignore - Express

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He added: "In this case, a number of incorrect patterns were identified sequentially (plantar fasciitis, gout, stress fracture), delaying a correct diagnosis." Although this was a "relatively rare phenomenon of acrometastasis of primary lung cancer to the foot as a presenting concern," it goes to show that this little known symptom should not be ignored. What are the most common symptoms of lung cancer? There are usually no early signs of lung cancer in its early stages, as it progresses the following common symptoms can emerge: A cough that persists after two to three weeks, or one that keeps getting worse Repeated chest infections

Study Estimates Impact of Targeted Treatments in NSCLC - AJMC.com Managed Markets Network

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Researchers reviewed clinical trial data of 19 FDA-approved treatments for non-small cell lung cancer. In an effort to estimate the years of life lost (YLL) with current non-small cell lung cancer (NSCLC) treatments based on molecular or biomarker subgroup, researchers evaluated all targeted therapies, chemotherapy, and immuno-oncology (IO) regimens approved by the FDA for these patients through March 3, 2021. Although the findings suggest targeted therapies have paved the way for progress in survival benefits for young patients with NSCLC and actionable mutations, "it is evident that these therapies still leave a wide gap in the YLL in these younger patients compared to generally older individuals with advanced NSCLC without targetable mutations," authors wrote. Previous molecular profiling of adenocarcinoma tissue has revealed the presence of targetable mutations, including epidermal growth factor receptor ( EGRF ), anaplastic lymphoma kinase ( ALK ) ROS1, MET, RET, BRAF, a...

Diseases That Mimic Lung Cancer: Symptoms & Diagnosis - Verywell Health

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Lung cancer is the second most common cancer diagnosed in both women and men in the United States. When detected at an earlier stage before it metastasizes (spreads), treatment for lung cancer is more likely to be successful.  Many people with lung cancer do not have symptoms until the disease has progressed. Early symptoms of lung cancer include persistent cough, chest pain, shortness of breath, unexplained weight loss, hoarseness, and frequent lung infections (e.g., bronchitis). Because other common diseases can mimic lung cancer, people who do experience early lung cancer symptoms may mistake them for another issue, such as an infection. It's important to see a healthcare provider promptly for any persistent and unusual symptoms, such as shortness of breath or a nagging cough.  This article will cover the diseases that mimic lung cancer, symptoms to watch out for,  and how to get an accurate diagnosis.  sorb...