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Lung Cancer News
Mar. 15, 2023 — A new study represents a first step towards generating highly detailed 3-dimensional maps of lung tumors using genetically engineered mouse ...
Mar. 13, 2023 — Scientists have discovered why breast cancer cells that have spread to the lungs may 'wake up' following years of sleep -- forming incurable secondary tumors. Their research reveals the ...
Feb. 13, 2023 — Researchers show how stimulating dendritic cells through certain pathways produces strong T cell activity against tumors and works in conjunction with immune checkpoint inhibitors to produce even ...
Feb. 1, 2023 — New data from a clinical trial shows improved rates of survival and reduced risk of recurrence in patients taking osimertinib, a targeted therapy for non-small cell lung cancer ...
Jan. 9, 2023 — A new study found that deleting a gene called KMT2D caused normal (basal) lung cells grown in complex cultures called organoids to transform into lung squamous carcinoma (LUSC) ...
Jan. 4, 2023 — A research team has shown that Sarunashi juice and its constituting component isoquercetin help prevent and reduce lung cancer in laboratory ...
Dec. 26, 2022 — Researchers report that they have developed a new experimental pipeline to combine bacterial therapy with current cancer drugs. Their study, which explores resistance to bacterial therapy at the ...
Dec. 1, 2022 — About 80% of people with cancer suffer from significant muscle wasting, or loss of muscle tissue, and 30% of these patients die from this condition. New research in mice finds that the severity of ...
Nov. 29, 2022 — While it may seem common knowledge that smoking is bad for your lungs, if and how ultrafine particles present in cigarette smoke impact the development and progression of lung cancer remains unclear. ...
Nov. 15, 2022 — Airway inflammation and emphysema are more common in marijuana smokers than cigarette smokers, according to a new study. Researchers said the difference may be due to the way that marijuana is smoked ...
Nov. 8, 2022 — Scientists investigating the mechanics of the early stages of lung cancer have identified a new potential treatment, which could also aid early detection of the disease. Levels of a key protein -- ...
Oct. 25, 2022 — A new study has revealed significant racial disparities in how quickly minorities with the most common form of lung cancer receive potentially lifesaving radiation therapy compared with their white ...
Oct. 6, 2022 — This year, about 200,000 people will be diagnosed with non-small-cell lung cancer, the second leading cause of death after cardiovascular disease. Researchers are working to improve the odds for ...
Sep. 28, 2022 — Despite significant advances, mortality from brain tumors remains high with five-year survival rates of 36%. More accurate diagnoses might improve the situation, but tissue biopsies are invasive and ...
Sep. 21, 2022 — The majority of the socioeconomic disparity, or deprivation gap, in cancer incidence could have been prevented in England between 2013 and 2017 if nobody had smoked, according to a new ...
Sep. 16, 2022 — In Germany, about ten per cent of all children are born before the 37th week of pregnancy and are thus considered premature. Many of these premature babies require help with breathing due to their ...
Sep. 13, 2022 — Researchers used extensive single-cell analysis to create a spatial map of tumor-infiltrating B cells and plasma cells in early-stage lung cancers, revealing new roles for these immune cells in ...
Sep. 13, 2022 — A new mechanism has been identified through which very small pollutant particles in the air may trigger lung cancer in people who have never smoked, paving the way to new prevention approaches and ...
Sep. 1, 2022 — About 30,000 cases of lung cancer occur in Spain each year. Mutations in KRAS oncogenes account for 10-15% of these cases, a subgroup against which there are still no effective therapies. Researchers ...
Aug. 31, 2022 — An experimental combination of two drugs halts the progression of small cell lung cancer, the deadliest form of lung cancer, according to a study in ...
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Lung Cancer Complications: What You Should Know
As lung cancer develops, a range of complications can occur.
They include:
Below, we look at each of these in more detail.
Blocked airwaysA tumor may grow into an airway in the lung and block it. This may lead to further complications, such as pneumonia and shortness of breath.
Blocked food pipeLung cancers that grow near a person's esophagus, or food pipe, can cause complications, making it painful or difficult for a person to swallow.
Spitting up bloodBlood in mucus or sputum can indicate lung cancer. However, this can also occur with tuberculosis, a pulmonary embolism, congestive heart failure, or intestinal damage.
According to a 2017 research review, 17.4% of cases of coughing up blood are due to cancer, while 25.8% stem from other respiratory diseases.
Any production of blood, whether through spitting or coughing, needs urgent medical attention. It may or may not be a sign of cancer, but a doctor can make a correct diagnosis.
Learn more about the causes of blood in sputum.
Facial swellingFacial swelling can sometimes be a complication of lung cancer. It can occur when tumors in the lungs block the flow of blood in a blood vessel known as the superior vena cava. Healthcare professionals refer to this as superior vena cava syndrome (SVCS).
Cancer is a common cause of SVCS, and most cases are due to lung cancer or non-Hodgkin lymphoma. SVCS may worsen when a person is lying down or raising both arms. Other symptoms of SVCS include:
In some cases, SVCS can be the first sign of cancer that appears.
A 2018 case study describes the experience of one person who approached a dermatologist about swelling around the eyes and a feeling of swelling in the face and throat. Diagnostic tests showed that the person had small-cell lung cancer (SCLC).
Excess fluid around the lungsExcess fluid around the lungs, or pleural effusion, is a buildup of fluid between the membranes that cover the lungs. The fluid can then press against the lungs, causing breathlessness.
In some cases, a doctor can drain the excess fluid to relieve symptoms. Alternatively, a doctor may reduce the pleural space by introducing irritants into it or by placing a catheter.
Higher risk of infectionSome 35–70% of deaths among people with lung cancer are due to infections.
This can happen because cancer compromises lung health, increasing the risk of bronchitis or pneumonia. Some types of treatment also reduce the effectiveness of the immune system.
If a person with lung cancer develops a fever, a sore throat, pain, or other symptoms of an infection, they should seek medical attention immediately.
A doctor may recommend treatment with antibiotics.
Learn about the links between pneumonia and lung cancer.
MetastasisAs cancer progresses, it spreads to other parts of the body. Cancer cells can move from the lungs to the liver, the bones, the brain, and other areas through the lymphatic system or bloodstream.
Possible symptoms include:
In the later stages, cancer may affect many parts of the body, but it will still be lung cancer if it began in the lungs.
Learn more about metastatic lung cancer.
Blood clotsThe American Cancer Society notes that people with cancer — especially lung cancer — may have a higher risk of blood clots. When cancer spreads to other parts of the body during metastasis, this can increase the risk as well.
Experts do not know exactly why this happens, but it may stem from tissue damage that occurs with cancer.
Heart and cardiovascular problemsAround 23% of people with lung cancer have cardiovascular disease. One reason may be that smoking is a strong risk factor for both diseases.
Even if a person does not already have heart disease, lung cancer can affect the heart and the cardiovascular system.
Lung cancer can also increase the risk of blood clots, which may lead to heart problems.
HypercalcemiaA person with hypercalcemia has high levels of calcium in their blood. This often occurs with metastatic lung cancer and other types of cancer.
A doctor may diagnose hypercalcemia when levels are as follows:
One reason is that the bloodstream reabsorbs calcium from the bones when cancer damages them. Changes to the hormonal system can also contribute.
Symptoms of hypercalcemia include fatigue, confusion, constipation, and nausea.
Learn more about hypercalcemia and its effects.
Spinal cord compressionUp to 5% of people with metastatic cancer experience spinal cord compression. Lung cancer is one of the types of cancer in which this is most likely to occur.
Metastatic spinal cord compression can happen when a vertebra collapses due to damage from cancer or when a tumor develops and presses on the spinal cord.
Anyone who experiences limb weakness, numbness, difficulty walking, a loss of bowel or bladder control, or pain in the chest or spine should contact their doctor.
NeuropathyNeuropathy is numbness and tingling in the hands and feet due to damaged nerve tissue. It can be a complication of lung cancer.
Neuropathy can occur when tumors are growing near the nerves in the arm or shoulder. A tumor compresses the nerves, leading to pain and weakness.
Here are some questions people often ask about lung cancer complications.
What are the complications of lung cancer?The complications of lung cancer include breathing difficulty, fluid around the lungs, and a higher risk of infections, blood clots, and neuropathy. Tumors and other symptoms may appear if cancer spreads. Living with cancer can also affect a person's mental health.
What are the complications of lung cancer treatment?The complications of treatment will depend on the treatment a person receives but may include a higher risk of blood clots and bone problems. Side effects may include nausea and vomiting, hair loss, and fatigue.
What happens when lung cancer gets worse?As lung cancer progresses, a person may find it harder to breathe. They may also have a higher risk of blood clots, infections, and other health concerns. If the cancer spreads to the liver, for instance, they may notice a yellowing of the whites of the eyes due to jaundice. If the cancer affects the brain, they may experience confusion, among other symptoms.
Lung Disease News
Aug. 11, 2023 — Yoga and breathing control practices, in combination with aerobic training, are particularly key exercises for asthmatic people seeking to improve their lung function, a new peer-reviewed study ...
Aug. 9, 2023 — New findings may lead to relapse-free treatment for a sizeable subgroup of lung cancer patients. In a study in mice, scientists have identified a biomarker that may help physicians select lung cancer ...
Aug. 8, 2023 — Overly active immune cells are often behind lung damage in diseases such as Covid-19. Researchers have developed an RNA agent for a lung spray that slows the activity of these cells, known as ...
July 25, 2023 — Having a food allergy as a baby is linked to asthma and reduced lung function later in childhood, according to a new ...
July 20, 2023 — Omega-3 fatty acids, which are abundant in fish and fish oil supplements, appear promising for maintaining lung health, according to new evidence from a large, multi-faceted study in healthy adults. ...
July 7, 2023 — The mucus in the airways is not as sticky, inflammation in the lungs significantly reduced: Triple combination therapy can achieve these positive, lasting effects in patients with cystic fibrosis ...
June 22, 2023 — Small-cell lung cancer is a particularly aggressive type of tumor with a consistently high mortality rate. In recent years, the research of scientists has significantly contributed to a better ...
June 8, 2023 — The largest and most comprehensive cell map of the human lung has been completed. The Human Lung Cell Atlas reveals the great diversity of cell types in the lung and shows key differences between ...
June 1, 2023 — Researchers have collaborated to refine a cell culture technology platform that grows genetically identical lung buds from human embryonic stem ...
May 24, 2023 — A new study has shown that human T cells have an important role to play in controlling ...
Apr. 21, 2023 — Storing donor lungs for transplant at 10 degrees Celsius markedly increases the length of time the organ can live outside the body according to new ...
Mar. 31, 2023 — A new type of nanoparticle can be administered to the lungs, where it can deliver messenger RNA encoding useful proteins. Researchers hope to use them to develop new treatments for cystic fibrosis ...
Mar. 28, 2023 — Researchers develop a 3D cell culture system to test how inhibiting fibroblast activities can help treat lung cancer. To simulate the tumor microenvironment and mimic real tissues, the team ...
Mar. 17, 2023 — A new study has revealed FDA-approved trametinib and entinostat (which is currently in clinical trials) can be given in tandem to produce fewer and smaller tumors in mice with LKB1-mutated non-small ...
Mar. 15, 2023 — A new study represents a first step towards generating highly detailed 3-dimensional maps of lung tumors using genetically engineered mouse ...
Mar. 13, 2023 — Scientists have discovered why breast cancer cells that have spread to the lungs may 'wake up' following years of sleep -- forming incurable secondary tumors. Their research reveals the ...
Mar. 10, 2023 — One in 10 adults suffer from the debilitating effects of chronic obstructive pulmonary disease (COPD). Research around a new breathing device developed by pulmonologists offers promise for improving ...
Mar. 9, 2023 — Congenital diaphragmatic hernia is one of the deadliest birth defects. To better understand and treat this condition in the future, researchers designed a new cell model in the laboratory and tested ...
Mar. 8, 2023 — Contracting a lower respiratory tract infection in early childhood is associated with a higher risk of dying from respiratory disease as an adult, according to new ...
Feb. 27, 2023 — New research reveals how the relationship between nerves and immune cells in the lungs can contribute to the development of allergic ...
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